William de la Pole, 1st Duke of Suffolk, (16 October 1396 – 2 May 1450), nicknamed Jackanapes, was an English magnate, statesman, and military commander during the Hundred Years' War. He became a favourite of the weak king Henry VI of England, and consequently a leading figure in the English government where he became associated with many of the royal government's failures of the time, particularly on the war in France. Suffolk also appears prominently in Shakespeare's Henry VI, parts 1 and 2.

He fought in the Hundred Years' War and participated in campaigns of Henry V, and then continued to serve in France for King Henry VI. He was one of the English commanders at the failed Siege of Orléans. He favoured a diplomatic rather than military solution to the deteriorating situation in France, a stance which would later resonate well with King Henry VI.

Suffolk became a dominant figure in the government, and was at the forefront of the main policies conducted during the period. He played a central role in organizing the Treaty of Tours (1444), and arranged the king's marriage to Margaret of Anjou. At the end of Suffolk's political career, he was accused of maladministration by many and forced into exile. At sea on his way out, he was caught by an angry mob, subjected to a mock trial, and beheaded.

His estates were forfeited to the Crown but later restored to his only son, John. His political successor was the Duke of Somerset.